DISTINCT CHANGES IN CREB PHOSPHORYLATION IN FRONTAL CORTEX AND STRIATUM DURING CONTINGENT AND NON-CONTINGENT PERFORMANCE OF A VISUAL ATTENTION TASK

Distinct changes in CREB phosphorylation in frontal cortex and striatum during contingent and non-contingent performance of a visual attention task

The cyclic-AMP response element binding protein (CREB) family of transcription factors has been implicated in numerous forms of behavioural plasticity.We investigated CREB phosphorylation along some nodes of corticostriatal circuitry such as frontal elf bar airpods case cortex (FC) and dorsal (caudate putamen, CPu) and ventral (nucleus accumbens, N

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Impact of two neighbouring ribosomal protein clusters on biogenesis factor binding and assembly of yeast late small ribosomal subunit precursors.

Many of the small ribosomal subunit proteins are required for the stabilisation of late small ribosomal subunit (SSU) precursors and for final SSU rRNA processing in S.cerevisiae.Among them are ribosomal proteins (r-proteins) which form a protein cluster around rpS0 (uS2) at the "neck" of the SSU (S0-cluster) and others forming a nearby protein clu

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Imaging Findings Associated with Cognitive Performance in Primary Lateral Sclerosis and Amyotrophic Lateral Sclerosis

Introduction: Executive dysfunction occurs in many patients with amyotrophic lateral sclerosis (ALS), but it has not been well studied in primary lateral sclerosis (PLS).The aims of this study were to (1) compare cognitive function in PLS to that in ALS patients, (2) explore the relationship between performance on specific cognitive tests and diffu

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